Cough Science News
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
Find all editions of Cough Science News below and get access to the latest cough science developments, publications, and interviews with cough experts.
This month’s roundup explores placebo effects in RCC trials, the role of interoception in chronic cough, and the cost burden of persistent symptoms, plus insights from Dr. Nadia Giannetti.
New key cough science publications, Actigraph x Hyfe partnership and more
This year marked significant progress in cough monitoring, solidifying cough as a valuable biomarker in diverse therapeutic areas
New findings on refractory chronic cough (RCC), pulmonary tuberculosis, and pulmonary fibrosis. Plus latest white papers by Hyfe.
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News Oct 1 - new studies on cough-related stress urinary incontinence, COVID-19 detection in vaccinated adults, and the effectiveness of anti-reflux surgery for chronic cough. Plus, expert discussions from Hyfe's Cough Science Forum and the latest on FDA regulations for cough monitoring technologies
Cough Science News, August 2024 - Explore studies on cough variability, acute cough duration, and the cost burden of chronic cough. Plus, discover the world’s most comprehensive collection of cinematic coughs and upcoming events in cough science
CougH Science News July 2024 - latest in cough science. Insights on cough detection algorithms, pulmonary fibrosis, asthma diagnosis from cough sounds, and more. Plus, watch expert discussions and stay updated on upcoming events
Hyfe Cough Science News, June 2024. Latest research on cough in fibrotic ILD, high-dose inhaled corticosteroids for chronic cough, and family physicians’ approaches to managing chronic cough. Plus, insights from leading researchers and upcoming events
Cough Science News May 2024 - studies on cough monitoring for COVID-19 surveillance, the effectiveness of codeine for chronic cough, factors in refractory cough in IPF, and more. Plus, insights from researchers and upcoming events
Hyfe Cough Science News, March 2024 - insights on chronic cough management in the UK, common triggers in cough hypersensitivity, and a review of treatments for refractory cough. Plus, expert Q&A and upcoming cough science events.
Key Takeaway:: This post hoc analysis examined which COPD patients are most likely to benefit from passive nighttime cough monitoring for early exacerbation detection. While baseline cough statistics couldn’t be predicted from patient data, a logistic regression model using age and CAT score achieved 85 percent accuracy in identifying patients who exhibit increased cough during exacerbations, key for alert system performance.
A randomized controlled trial showed that internet-based behavioral cough suppression therapy (IBCST) significantly improved cough-related quality of life in patients with refractory chronic cough, with results comparable to in-person therapy.: Passive cough monitoring systems are promising tools for identifying COPD exacerbations early. This study shows that patient stratification can significantly improve alert accuracy. It highlights the potential of targeted deployment for scalable and effective COPD management.
Why It Matters:
Patients with chronic cough have limited treatment options. BCST is highly effective but often underutilized due to limited specialist availability and long referral pathways. Delivering BCST online makes it more accessible, especially for patients in rural areas, and opens the door to future digital therapeutic adaptations.
Key Takeaway: This study, part of the I3LUNG project, used machine learning and deep learning models to analyze forced cough recordings from NSCLC patients and healthy individuals. The deep learning model achieved 95% accuracy and 100% specificity in distinguishing patients, and cough features also varied by smoking status and presence of lung metastases.
By augmenting a validated cough-based alert mechanism with a new fast-response component, researchers improved detection sensitivity to 86% with manageable false alerts (~1.5 per year). Importantly, 80% of early alerts gave 6+ days of lead time, offering valuable room for intervention.: This research suggests that forced cough might be a non-invasive, AI-powered biomarker for early lung cancer detection and potentially for monitoring disease progression, however, much more work needs to be done for a viable solution to be validated and deployed.
Why It Matters
Early detection of COPD exacerbations is critical for reducing hospitalizations (including readmissions), and improving recovery. This study shows that interpretable, rule-based bedside cough monitoring can provide patients and clinicians with actionable, personalized insights, helping establish trust in digital tools for self-management and telehealth.
Key Takeaway In a Northern European population-based study, 30% of people with chronic dry cough and over 50% with chronic productive cough reported voice problems, significantly higher than those without cough. Both chronic cough and voice problems were independently linked to poorer general health, and when co-occurring, their negative effects were additive. Chronic cough, but not voice problems, was associated with increased sick leave.
Why It Matters This is the first large-scale evidence showing that voice problems are not only common in chronic cough but also compound its impact on health. The findings highlight the need for clinicians to address cough-related vocal symptoms alongside respiratory care to improve quality of life and outcomes.
The study highlights the potential of wearable-based cough tracking to provide an objective, continuous signal for monitoring pulmonary fibrosis dynamics, offering a complementary layer of insight beyond traditional patient questionnaires.
Over the past few months, our experts have been sharing how Hyfe is reshaping the landscape of cough measurement and treatment. These short Q&As spotlight the innovation behind our platforms:
We’re looking forward to the ERS Congress 2025 in Amsterdam this September. Our academic and industry collaborators have several presentations lined up:
Our CEO, Tamsin Chislett, and Digital Health Lead, Dr. Mindaugas Galvosas, will be there to present a few posters and recent insights from Hyfe. To connect at ERS, send a message to mindaugas@hyfe.com.
