53
Research Trials
20
Peer-reviewed publications
16
Clinical Conditions
At CHEST 2025, held in Chicago, Illinois, Laurie Slovarp, PhD, CCC-SLP, professor at the University of Montana and certified speech pathologist, presented a poster on the development of a digital therapeutic designed to improve access to behavioral cough suppression therapy for patients with refractory chronic cough.
A large-scale trial examining the effect of azithromycin on the relationship between oesophageal function and cough as evaluated by Hyfe's cough monitoring technology in respiratory disease is feasible and acceptable to patients.
This study used Hyfe's wearable cough monitor during a 7-day run in, 28-day treatment, and 14-day follow-up period in patients with chronic bronchitis.
Periods of intense coughing (termed bouts, epochs or bursts) are particularly problematic for some coughers and may not be reflected by simply counting the number of coughs per day. This study explored how varying the definition of bouts yield different impressions of cough severity.
The Hyfe “CoughMonitor” is a wrist-worn device thatcaptures sound through its microphone and processesthat sound on device to detect and quantify coughingover time; the device ingests continuous audio andoutputs the timestamps of all of the coughs that itdetects. To assess the CoughMonitor’s accuracy, onemust compare its output (when the device reportsthat coughing occurred) with objective ground truth(when trained human annotators report that coughingoccurred).
A perfectly accurate device would detectevery human annotated cough as such and would notidentify anything else as a cough.This paper describes a small pilot study aimed atquantifying the accuracy of an earlier version of theHyfe CoughMonitor and, in so doing, demonstrates theanalytical approach and data presentation that will beemployed in the subsequent FDA enabling study.
