Long-COVID severe refractory cough: discussion of a case with 6-week longitudinal cough characterization

Summary

This publication suggests that continuous cough monitoring can be used in remote patient monitoring, with a case of a patient with Long-COVID presented.

Long coronavirus disease (COVID) refers to an array of variable and fluctuating symptomsexperienced after acute illness, with signs and symptoms that persist for 8–12 weeks andare not otherwise explicable. Cough is the most common symptom of acute COVID-19, butcough may persist in some individuals for weeks or months after recovery from acute phase.Long-COVID cough patients may get stigmatised because of the public fear of contagionand reinfection. However, clinical characteristics and longitudinal course of long-COVIDcough have not been reported in detail, and evidence-based treatment is also lacking. In thispaper, we describe a case of long-COVID severe refractory cough with features of laryngealhypersensitivity and dysfunction. We characterized cough using patient-reported outcomesand engaged in continuous cough frequency monitoring. Through the case study, we discusspotential mechanisms, managements, and clinical implications of long-COVID refractorycough problems.